Nenad Pavin Group

M. Šoštar, M. Marinović, V. Filić, N. Pavin, I. Weber
Oscillatory dynamics of Rac1 activity in Dictyostelium discoideum amoebae
PLOS Computational Biology [View PDF]
https://doi.org/10.1371/journal.pcbi.1012025

I. Sigmund, D. Božan, I. Šarić, and N. Pavin
Mechanisms of Chromosome Positioning During Mitosis
PRX Life [View PDF]
https://doi.org/10.1103/PRXLife.2.043017

I. Ban, L. Tomašić, M. Trakala, I.M. Tolić and N. Pavin
Proliferative advantage of specific aneuploid cells drives evolution of tumor karyotypes.
Biophys J 122, 632-645 (2023). [View PDF]
Earlier version of the manuscript is available online at: bioRxiv, doi.org/10.1101/2022.04.14.488382.

J. Matković, S. Ghosh, M. Ćosić, S. Eibes, M. Barišić, N. Pavin and I.M. Tolić
Kinetochore- and chromosome-driven transition of microtubules into bundles promotes spindle assembly.
Nat Commun 13, 7307 (2022). [View PDF]

P. Risteski, D. Božan, M. Jagrić, A. Bosilj, N. Pavin and I.M. Tolić
Length-dependent poleward flux of sister kinetochore fibers promotes chromosome alignment.
Cell Reports 40, 111169 (2022) [View PDF]

A. Ivec, M. Trupinić, I.M. Tolić and N. Pavin
Oblique circle method for measuring the curvature and twist of mitotic spindle microtubule bundles.
Biophys J 120, 3641-3648 (2021). [View PDF]

P. Risteski, M. Jagrić, N. Pavin and I.M. Tolić
Biomechanics of chromosome alignment at the spindle midplane.
Curr Biol 31, R574-R585 (2021). [View PDF]

I.M. Tolić and N. Pavin
Mitotic spindle: Lessons from theoretical modeling.
Mol Biol Cell 32, 218–222 (2021). [View PDF]

N. Pavin and I.M. Tolić
Mechanobiology of the Mitotic Spindle.
Dev Cell 56, 192-201 (2021). [View PDF]

M. Prelogović, L. Winters, A. Milas, I.M. Tolić, and N. Pavin
Pivot-and-bond model explains microtubule bundle formation.
Phys Rev E 100, 012403 (2019). [View PDF]
Earlier version of the manuscript is available online at: bioRxiv, doi:10.1101/157719.

L. Winters, I. Ban, M. Prelogović, I. Kalinina, N. Pavin., I.M. Tolić.
Pivoting of microtubules driven by minus-end-directed motors leads to spindle assembly.
BMC Biology 17:42 (2019). [View PDF]

I.M. Tolic, M. Novak, N. Pavin.
Helical Twist and Rotational Forces in the Mitotic Spindle.
Biomolecules 9, 132 (2019). [View PDF]

M. Novak, B. Polak, J. Simunić, Z. Boban, B. Kuzmić, A. Thomae, I.M. Tolić, N. Pavin.
The mitotic spindle is chiral due to torques within microtubule bundles.
Nat. Commun. 9, 3571 (2018). [View PDF]
Pre-print of the paper is available online at: bioRxiv, doi:10.1101/167437.

I. Jelenić, A.M. Selmecki, L. Laan, N. Pavin.
Spindle Dynamics Model Explains Chromosome Loss Rates in Yeast Polyploid Cells.
Front Genet 9, 296 (2018). [View PDF]
Pre-print of the paper is available online at: bioRxiv, doi:10.1101/204230.

A.H. Klemm, A. Bosilj, M Glunčić, N. Pavin, I.M. Tolić.
Metaphase kinetochore movements are regulated by kinesin-8 motors and microtubule dynamic instability.
Mol Biol Cell 29, 1332-1345 (2018) [View PDF]

K. Vukušić, R. Buda, A. Bosilj, A. Milas, N. Pavin, I.M. Tolić.
Microtubule Sliding within the Bridging Fiber Pushes Kinetochore Fibers Apart to Segregate Chromosomes.
Dev Cell 43, 11-23 (2017). [View PDF]

G .Cojoc, A.M. Florescu, A. Krull, A. Klemm, N. Pavin, F. Julicher, I.M. Tolić.
Paired arrangement of kinetochores together with microtubule pivoting and dynamics drive kinetochore capture in meiosis I.
Sci Rep 6, 25736 (2016). [View PDF]

N. Pavin and I.M. Tolić.
Self-Organization and Forces in the Mitotic Spindle.
Annu Rev Biophys 45, 279-298 (2016). [View PDF]

I.M. Tolić and N. Pavin.
Bridging the gap between sister kinetochores.
Cell Cycle, 15 1169-1179 (2016). [View PDF]

G. Cojoc, E. Roscioli, L. Zhang, A. Garcia-Ulloa, J.V. Shah, M.W. Berns, N. Pavin, D. Cimini, I.M. Tolić, and J. Gregan.
Laser microsurgery reveals conserved viscoelastic behavior of the kinetochore.
J Cell Biol 212, 767-776 (2016). [View PDF]
Comment by Simon Cabello, Yannick Gachet and Sylvie Tournier

J. Kajtez, A. Solomatina, M. Novak, B. Polak, K. Vukušić, J. Rudiger, G. Cojoc, A. Milas, I Šumanovac Šestak, P. Risteski, F. Tavano, A.H. Klemm, E. Roscioli, J. Welburn, D. Cimini, M. Glunčić, N. Pavin, I.M. Tolić.
Overlap microtubules link sister k-fibers and balance the forces on bioriented kinetochores.
Nat. Commun. 7, 10298 (2016). [View PDF]

M. Glunčić, N. Maghelli, A. Krull, V. Krstić, D. Ramunno-Johnson, N. Pavin, and I.M. Tolić.
Kinesin-8 Motors Improve Nuclear Centering by Promoting Microtubule Catastrophe.
Phys. Rev. Lett. 114, 078103 (2015). [View PDF]

N. Pavin, I.M. Tolić-Norrelykke.
Swinging a sword: how microtubules search for their targets.
Syst Synth Biol 8, 179-186 (2014) [View PDF]

R. Ma, L. Laan, M. Dogterom, N. Pavin and F. Julicher.
General theory for the mechanics of confined microtubule asters.
New J Phys 16, 013018 (2014) [View PDF]

N. Pavin, I.M. Tolić-Norrelykke.
Dynein, microtubule and cargo: a menage à trois.
Biochem Soc Trans 41, 1731-1735 (2013) [View PDF]

V. Ananthanarayanan, M. Schattat, S.K. Vogel, A. Krull, N. Pavin, I.M. Tolić-Norrelykke.
Dynein motion switches from diffusive to directed upon cortical anchoring.
Cell 153, 1526-1536 (2013) [View PDF]

I. Kalinina, A. Nandi, P. Delivani, M Chacon, A. Klemm, D. Ramunno-Johnson, A. Krull, B. Lindner, N. Pavin, I.M. Tolić-Norrelykke.
Pivoting of microtubules around the spindle pole accelerates kinetochore capture.
Nat Cell Biol 15, 82-87 (2013). [View PDF]

N. Pavin, L. Laan, R. Ma, M. Dogterom and F. Julicher.
Positioning of microtubule organizing centers by cortical pushing and pulling forces.
New J Phys 14, 105025 (2012). [View PDF]

L. Laan, N. Pavin, J.Husson, G. Romet-Lemonne, M. van Duijn, M. Preciado Lopez, R. D. Vale, F. Julicher, S. L. Reck-Peterson and M. Dogterom.
Cortical Dynein Controls Microtubule Dynamics to Generate Pulling Forces that Position Microtubule Asters.
Cell 148, 502 (2012). [View PDF]

C. Leduc, N. Pavin, F. Julicher, S. Diez.
Collective Behavior of Antagonistically Acting Kinesin-1 Motors.
Phys Rev Lett 105, 128103 (2010). [View PDF]

S. Vogel, N. Pavin, N. Maghelli, F. Julicher, I.M. Tolić-Norrelykke.
Self-Organization of Dynein Motors Generates Meiotic Nuclear Oscillations.
PLoS Biology 7, 918-928 e1000087 (2009). [View PDF]

S. Vogel, N. Pavin, N. Maghelli, F. Julicher, I.M. Tolić-Norrelykke.
Microtubules and motor proteins: Mechanically regulated self-organization in vivo.
Eur Phys J ST 178, 57 (2009). [View PDF]

V. Paar, N. Pavin, I. Basar, M. Rosandi, M. Glunčić, N. Paar
Hierarchical structure of cascade of primary and secondary periodicities in Fourier power spectrum of alphoid higher order repeats.
BMC Bioinformatics 9, 466 (2008). [View PDF]

T. Engelsfeld, F. Šumanovac, N. Pavin
Investigation of underground cavities in a two-layer model using the refraction seismic method.
Near Surface Geophysics. 6, 221-231 (2008). [View PDF]

V. Krstić, Z. Maglica, H. Čipčić Paljetak, B. Podobnik, N. Pavin
Min-Protein Oscillations in E. coli: Three-Dimensional Off-Lattice Stochastic Reaction-Diffusion Model.
J Stat Phys 128, 5 (2007), [View PDF]

M. Rosandic, V. Paar, I. Basar, M. Glunčić, N. Pavin, I. Pilas
CENP-B box and pJ alpha sequence distribution in human alpha satellite higher-order repeats (HOR).
Chromosome Research 14, 735-753 (2006) [View PDF]

V. Lopac, I. Mrkonjić, N. Pavin and D. Radić
Chaotic dynamics of the elliptical stadium billiard in the full parameter space.
Physica D 217, 88-101 (2006), [View PDF]

N. Pavin, H. Čipčić Paljetak, V. Krstić
Min-protein oscillations in Escherichia coli with spontaneous formation of two-stranded filaments in a three-dimensional stochastic reaction-diffusion model.
Phys Rev E 73, 021904 (2006), [View PDF]

V. Paar, N. Pavin, M. Rosandić, M. Glunčić, I. Basar, Robert Pezer, and S. Durajlija-Žinić
ColorHOR – novel graphical algorithm for fast scan of alpha satellite higher-order repeats and HOR annotation for GenBank sequence of human genome.
Bioinformatics 21 (2005) 846-852 [View PDF]

V. Paar, N. Pavin, I. Basar, M. Rosandić, I. Luketin, and S. Durajlija-Žinić
Spectral Densities and Frequencies in the Power Spectrum of Higher Order Repeat Alpha Satellite in Human DNA Molecule.
Croatica Chemica Acta 77 (2004) 73-81 [View PDF]

V. Paar and N. Pavin
Overlapping of two truncated crisis scenarios: Generator of peaks in mean lifetimes of chaotic transients.
Phys Rev E 68 (2003) 036222.

V. Paar and N. Pavin
Regularity-Partial Chaos-Regularity Transition and Overlapped KAM Scenarios in a Conservative System of Two Linearly Coupled Double-Well Oscillators
Modern Physics Letters B 17 (2003) 941-948.

Marija Rosandić, Vladimir Paar, Matko Glunčić, Ivan Basar, Nenad Pavin
Key-string Algorithm – Novel Approach to Computational Analysis of Repetitive Sequences in Human Centromeric DNA.
Croatian Medical Journal 44 (2003) 386-406.

V. Paar, N. Pavin, A. Rubčić, J. Rubčić
Power law and fractality for nuclear stability, atomic weights and molecular weights.
Chaos Solitons & Fractals, 14 (2002) 901-916.

V. Paar, N. Pavin, A. Rubčić, J. Rubčić
Fractality of abundance-weighted N,Z-chart of isotopes and systematics of atomic weights of chemical elements.
Croatica Chemica Acta, 75 (2002) 121-129.

V. Paar, N. Pavin, M. Rosandic
Link between truncated fractals and coupled oscillators in biological systems.
Journal of Theoretical Biology, 212 (2001) 47-56.

V. Paar, N. Pavin, A. Rubčić, J. Rubčić, N. Trinajstić
Scale-invariant power law and fractality for molecular weights.
Chemical Physics Letters 336 (2001) 129-134.

V. Paar, N. Pavin, M. Rosandić
Energy dependence of self-similarity truncation in a system of weakly coupled dissipative oscillators relevant for biological systems.
Fizika A, 10 (2001) 95-104.

V. Paar, N. Pavin
Overlapped KAM patterns for linearly coupled asymmetric oscillators.
Fizika A, 9 (2000) 95-104.

V. Paar, N. Pavin
Relation between uncertainty exponent and mean lifetime of chaotic transient for map on annulus.
Mod Phys Lett 14 (2000) 167-172.

V. Paar, N. Pavin, N.Paar and B. Novaković
Nonlinear dynamics of a single-degree robot model Part 2: Onset of chaotic transients.
Robotica, 18 (2000) 201-208.

V. Paar and N. Pavin
Intermingled fractal Arnold tongues.
Phys Rev E, 57 (1998) 1544-1549.

V. Paar and N. Pavin
Missing preimages for chaotic logistic map with a hole.
Fizika B6 (1997) 23-35.

V. Paar and N. Pavin
Discontinuous Pattern of cumulative separation between orbits of chaotic transient.
Phys Lett A 235 (1997) 139-144.

V. Paar and N. Pavin
Dependence of lifetimes of chaotic transients in the weakly dissipative Duffing oscillator on numerical precision and external noise.
Physica A 242 (1997) 166-174.

V. Paar and N. Pavin
Bursts in average lifetime of transients for chaotic logistic map with a hole.
Phys Rev E 55 (1997) 4112-4115.

V. Paar and N. Pavin
Sensitive dependence of lifetimes of chaotic transient on numerical accuracy for a model with dry friction and frequency dependent driving amplitude.
Mod Phys Lett 10 (1996) 153-159.

V. Paar, N. Pavin, N.Paar and B. Novaković
Nonlinear regular dynamics of a single-degree robot model.
Robotica 14 (1996) 423-431.